{"product_id":"epidermal-growth-factor-egf","title":"Epidermal Growth Factor (EGF) (GR001)","description":"\u003ctable style=\"border-collapse: collapse;\" width=\"100%\" data-mce-style=\"border-collapse: collapse;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"border: 1px solid black; width: 46.6089%; text-align: center;\" data-mce-style=\"border: 1px solid black; width: 46.6089%; text-align: center;\"\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0632\/0367\/2281\/files\/EGF_GR001__PI.pdf?v=1690246475\" target=\"_blank\"\u003e\u003cstrong\u003e제품 설명서 (PDF 파일 다운로드)\u003c\/strong\u003e\u003c\/a\u003e\u003c\/td\u003e\n\u003ctd style=\"border: 1px solid black; width: 53.3911%; text-align: center;\" colspan=\"2\" data-mce-style=\"border: 1px solid black; width: 53.3911%; text-align: center;\"\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0632\/0367\/2281\/files\/EGF_GR001_GHS_SDS_welgene.pdf?v=1698107184\" target=\"_blank\"\u003e\u003cstrong\u003eMSDS (PDF 파일 다운로드)\u003c\/strong\u003e\u003c\/a\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eEpidermal Growth Factor (EGF)\u003cbr\u003e\u003c\/strong\u003erecombinant, Human\u003cbr\u003eexpressed in E.Coli\u003c\/p\u003e\n\u003cp\u003eCatalog Number\u003cbr\u003e\u003cstrong\u003eGR 001-010 (10ug)\u003cbr\u003e\u003c\/strong\u003e\u003cstrong\u003eGR 001-050 (50ug)\u003cbr\u003e\u003c\/strong\u003e\u003cstrong\u003eGR 001-200 (200ug)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eStorage Temperature -5 ~ -20°C\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePrecautions\u003cbr\u003e\u003c\/strong\u003eFor \u003cem\u003eIn Vitro \u003c\/em\u003eUse Only\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProduct Description\u003cbr\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eEpidermal Growth Factor (EGF) is a 6 kDa protein having three intramolecular disulfide bonds.The main function of the Epidermal Growth Factor (EGF) is to promote cell growth, proliferation, and differentiation in various tissues. When EGF binds to its receptor, the EGF receptor (EGFR), it triggers a cascade of signaling events that activate intracellular pathways, such as the Ras\/MAPK and PI3K\/AKT pathways. These pathways regulate cellular processes such as DNA synthesis, cell cycle progression, cell migration, and survival.\u003c\/p\u003e\n\u003cp\u003eEGF is involved in various physiological and pathological processes, such as wound healing, tissue repair, cancer, and inflammation. In wound healing and tissue repair, EGF stimulates the growth and migration of epithelial cells, essential for re-epithelializing injured tissues. EGF is often overexpressed or dysregulated in cancer, leading to uncontrolled cell growth and proliferation.\u003c\/p\u003e\n\u003cp\u003eEGF also plays a role in embryonic development, where it regulates cell proliferation, differentiation, and morphogenesis. In addition, EGF has been shown to have potential therapeutic applications in the treatment of certain diseases, such as chronic wounds, ulcers, and dermatitis, where it can promote tissue regeneration and healing\u003cstrong\u003e\u003cbr\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProduct Information\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eAlternative Names :\u003cbr\u003e\u003c\/strong\u003e\u003cspan style=\"font-size: 0.875rem;\"\u003eEpidermal growth factor, epithelial growth factor, EGF, HOMG4, URG\u003cbr\u003e\u003c\/span\u003e\u003cstrong\u003eSpecies :\u003c\/strong\u003e Human\u003cbr\u003e\u003cstrong\u003eSource :\u003c\/strong\u003e E. Coli\u003cbr\u003e\u003cstrong\u003ePredicted Molecular Mass :\u003c\/strong\u003e 6.3 kDa\u003cbr\u003e\u003cstrong\u003eAmino Acid Sequence :\u003cbr\u003e\u003c\/strong\u003eNSDSECPLSHDGYCLHDGVCMYIEALDKYACNCVVGYIGERCQYRDLKWWELR\u003cbr\u003e\u003cstrong\u003eFormulation : \u003cbr\u003e\u003c\/strong\u003eLyophilized from a sterile-filtered aqueous solution containing 20mM Sodium Phosphate, pH 7.0.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cbr\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProduct Specifications\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBiological activity :\u003cbr\u003e\u003c\/strong\u003eThe EC\u003csub\u003e50\u003c\/sub\u003e ≤ 1.0 ng\/mL as determined by a cell proliferation assay using BALB\/ 3T3 cells.\u003cbr\u003e\u003cstrong\u003ePurity : \u003cbr\u003e\u003c\/strong\u003e≥ 95% purity by SDS-PAGE\u003cbr\u003e\u003cstrong\u003eEndotoxin : \u003cbr\u003e\u003c\/strong\u003e≤ 0.5 EU\/mg protein by LAL(Limulus amebocyte lysate) analysis method.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePreparation and Storage\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eStorage :\u003cbr\u003e\u003c\/strong\u003eStore at -5 °C to -20 °C.\u003cbr\u003e\u003cstrong\u003eStability : \u003cbr\u003e\u003c\/strong\u003eStable as supplied for 12 months from date of receipt.\u003cbr\u003e\u003cstrong\u003ePreparation : \u003cbr\u003e\u003c\/strong\u003eCentrifuge vial before opening. Reconstitute the product in sterile water to at least 0.1 mg\/mL by pipetting the solution down the sides of the vial. Do not vortex\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDATA\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e(A) The biological activity of Human Recombinant EGF was tested by its ability to promote the proliferation of BALB\/c 3T3 cells. Cell proliferation was measured using a fluorometric assay method. The EC50 is defined as the effective concentration of the growth factor at which cell proliferation is at 50% of maximum. The EC50 in the under example is 0.42 ng\/mL.\u003cbr\u003e(B) Human Recombinant EGF was resolved with SDS-PAGE under and visualized by Coomassie Blue staining. Human Recombinant EGF has a predicted molecular mass of 6.3 kDa.\u003c\/p\u003e\n\u003cp\u003e\u003cimg alt=\"\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0632\/0367\/2281\/files\/EpidermalGrowthFactor_2048x2048.jpg?v=1689735188\"\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e","brand":"Welgene","offers":[{"title":"10ug - 본사 문의","offer_id":43992816058585,"sku":null,"price":72000.0,"currency_code":"KRW","in_stock":true},{"title":"50ug - 본사 문의","offer_id":43992816091353,"sku":null,"price":178000.0,"currency_code":"KRW","in_stock":true},{"title":"200ug - 본사 문의","offer_id":43992816320729,"sku":"","price":224000.0,"currency_code":"KRW","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0632\/0367\/2281\/files\/GR001_new.jpg?v=1716276057","url":"https:\/\/en.welgene.com\/ko\/products\/epidermal-growth-factor-egf","provider":"Welgene","version":"1.0","type":"link"}