{"product_id":"basic-fibroblast-growth-factor-bfgf","title":"Basic Fibroblast Growth Factor (bFGF) (GR003)","description":"\u003ctable style=\"border-collapse: collapse;\" width=\"100%\" data-mce-style=\"border-collapse: collapse;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"border: 1px solid black; width: 46.6089%; text-align: center;\" data-mce-style=\"border: 1px solid black; width: 46.6089%; text-align: center;\"\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0632\/0367\/2281\/files\/bFGF_GR003__PI.pdf?v=1690246476\" target=\"_blank\"\u003e\u003cstrong\u003e제품 설명서 (PDF 파일 다운로드)\u003c\/strong\u003e\u003c\/a\u003e\u003c\/td\u003e\n\u003ctd style=\"border: 1px solid black; width: 53.3911%; text-align: center;\" colspan=\"2\" data-mce-style=\"border: 1px solid black; width: 53.3911%; text-align: center;\"\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0632\/0367\/2281\/files\/bFGF_GR003_GHS_SDS_welgene.pdf?v=1698107183\" rel=\"noopener noreferrer\" target=\"_blank\"\u003e\u003cstrong\u003eMSDS (PDF 파일 다운로드)\u003c\/strong\u003e\u003c\/a\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBasic Fibroblast Growth Factor (bFGF)\u003cbr\u003e\u003c\/strong\u003erecombinant, Human\u003cbr\u003eexpressed in E.Coli\u003c\/p\u003e\n\u003cp\u003eCatalog Number\u003cbr\u003e\u003cstrong\u003eGR 003-010 (10ug)\u003cbr\u003e\u003c\/strong\u003e\u003cstrong\u003eGR 003-050 (50ug)\u003cbr\u003e\u003c\/strong\u003e\u003cstrong\u003eGR 003-200 (200ug)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eStorage Temperature -5 ~ -20°C\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePrecautions\u003cbr\u003e\u003c\/strong\u003eFor \u003cem\u003eIn Vitro \u003c\/em\u003eUse Only\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProduct Description\u003cbr\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eFibroblast Growth Factor, basic (syn.; FGF-2; HBGF-2) is 55% homology to FGF acidic and prototypic member of the fibroblast growth factor family. Fibroblast growth factor 2, also known as basic fibroblast growth factor (bFGF) and FGF-β, is a growth factor and signaling protein encoded by the FGF2 gene. It binds to specific fibroblast growth factor receptor (FGFR) proteins, a family of closely related molecules, and through them has a wide range of mitotic and cell survival activities, exerting a variety of biological effects including cell proliferation, differentiation, survival and apoptosis.\u003c\/p\u003e\n\u003cp\u003eIt supports the maintenance of undifferentiated human pluripotent stem cells, stimulates human pluripotent stem cells to form neural rosettes, and improves proliferation of human mesenchymal stem cells and enhances chondrogenic differentiation. Also it supports the maintenance of undifferentiated human pluripotent stem cells, stimulates human pluripotent stem cells to form neural rosettes, and improves proliferation of human mesenchymal stem cells and enhances chondrogenic differentiation\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProduct Information\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eAlternative Names :\u003cbr\u003e\u003c\/strong\u003e\u003cspan style=\"font-size: 0.875rem;\"\u003eBasic fibroblast growth factor, bFGF, FGF-β, FGF2, HBGF-2\u003cbr\u003e\u003c\/span\u003e\u003cstrong\u003eSpecies :\u003c\/strong\u003e Human\u003cbr\u003e\u003cstrong\u003eSource :\u003c\/strong\u003e E. Coli\u003cbr\u003e\u003cstrong\u003ePredicted Molecular Mass :\u003c\/strong\u003e 16.4 kDa\u003cbr\u003e\u003cstrong\u003eAmino Acid Sequence :\u003cbr\u003e\u003c\/strong\u003ePALPEDGGSGAFPPGHFKDPKRLYCKNGGFFLRIHPDGRVDGVREKSDPHIKLQLQAEERGVVSIKGVCANRYLAMKEDGRLLASKCVTDECFFFERLESNNYNTYRSRKYTSWYVALKRTGQYKLGSKTGPGQKAILFLPMSAKS\u003cbr\u003e\u003cstrong\u003eFormulation : \u003cbr\u003e\u003c\/strong\u003eLyophilized from a sterile-filtered aqueous solution containing 20mM Sodium Phosphate, pH 7.0\u003cbr\u003e\u003cstrong\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProduct Specifications\u003cbr\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBiological activity :\u003cbr\u003e\u003c\/strong\u003eThe EC\u003csub\u003e50\u003c\/sub\u003e ≤ 2.0 ng\/mL as determined by a cell proliferation assay using BALB\/ 3T3 cells.\u003cbr\u003e\u003cstrong\u003ePurity : \u003cbr\u003e\u003c\/strong\u003e≥ 95% purity by SDS-PAGE\u003cbr\u003e\u003cstrong\u003eEndotoxin : \u003cbr\u003e\u003c\/strong\u003e≤ 0.5 EU\/mg protein by LAL(Limulus amebocyte lysate) analysis method.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePreparation and Storage\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eStorage :\u003cbr\u003e\u003c\/strong\u003eStore at -5 °C to -20 °C.\u003cbr\u003e\u003cstrong\u003eStability : \u003cbr\u003e\u003c\/strong\u003eStable as supplied for 12 months from date of receipt.\u003cbr\u003e\u003cstrong\u003ePreparation : \u003cbr\u003e\u003c\/strong\u003eCentrifuge vial before opening. Reconstitute the product in sterile water to at least 0.1 mg\/mL by pipetting the solution down the sides of the vial. Do not vortex\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDATA\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e(A) The biological activity of Human Recombinant bFGF was tested by its ability to promote the proliferation of BALB\/c 3T3 cells. Cell proliferation was measured using a fluorometric assay method. The EC50 is defined as the effective concentration of the growth factor at which cell proliferation is at 50% of maximum. The EC50 in the under example is 1.33 ng\/mL.\u003cbr\u003e(B) Human Recombinant bFGF was resolved with SDS-PAGE under and visualized by Coomassie Blue staining. Human Recombinant bFGF has a predicted molecular mass of 16.4 kDa.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0632\/0367\/2281\/files\/BasicFibroblastGrowthFactor_bFGF_2048x2048.jpg?v=1689742305\" alt=\"\"\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e","brand":"Welgene","offers":[{"title":"10ug - 본사 문의","offer_id":43992899977433,"sku":null,"price":87000.0,"currency_code":"KRW","in_stock":true},{"title":"50ug - 본사 문의","offer_id":43992900010201,"sku":null,"price":174000.0,"currency_code":"KRW","in_stock":true},{"title":"200ug - 본사 문의","offer_id":43992900042969,"sku":null,"price":328000.0,"currency_code":"KRW","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0632\/0367\/2281\/files\/GR003_best.jpg?v=1739508802","url":"https:\/\/en.welgene.com\/ko\/products\/basic-fibroblast-growth-factor-bfgf","provider":"Welgene","version":"1.0","type":"link"}